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Creates advanced therapeutic and diagnostic tools by exploiting nanoscale materials in a safe and environmentally responsible manner

We are some of Tomorrow’s Labs

CORE MEMBERS

The NanoInflammation Lab studies how nanomaterials may cause inflammation or be used to modulate inflammation and control disease
The NanoCell Biology Lab unveils interactions of nanomaterials with living cells and their structural compartments
The NanoOmics Lab aims to harness the interactions of nanomaterials with biological matter for the discovery of novel biomarkers
The NanoTherapeutics Lab exploits the unique properties of nanoparticles to develop clinically translatable advanced medicines

AFFILIATE MEMBERS

Innovative neuroscience technologies, including wide bandwidth electrophysiology, multi-modal imaging and gene therapy
The Nanomedicine Lab designs, fabricates and characterizes advanced nanomaterials for biomedical and clinical use

RECENT PUBLICATIONSVIEW ALL

Nature Reviews Materials, 2024, in press

In vivo biomolecule corona and the transformation of a foe into an ally for nanomedicine

Marilena Hadjidemetriou, Morteza Mahmoudi*, Kostas Kostarelos*

FULL ABSTRACT

Nature Nanotechnology, 2024, in press [https://doi.org/10.1038/s41565-023-01572-3]

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

Jack Andrews^, Shruti Joshi^, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert, Livia Crica, Neus Lozano, Emmanuel Okwelogu, Jennifer Raftis, Lorraine Bruce, Craig Poland, Rodger Duffin, Paul Fokkens, John Boere, Daan Leseman, Ian Megson, Phil D. Whitfield, Kerstin Ziegler, Seshu Tammireddy, Marilena Hadjidemetriou, Cyrill Bussy, Flemming Cassee, David Newby, Kostas Kostarelos*, Mark Miller*

FULL ABSTRACT

ACS Nano, 2024, published online

Environmental and health impacts of graphene and other two-dimensional materials: a Graphene Flagship perspective

Hazel Lin, Tina Buerki-Thurnherr, Jasreen Kaur, Peter Wick, Marco Pelin, Aurelia Tubaro, Fabio Candotto Carniel, Mauro Tretiach, Emanuel Flahaut, Daniel Iglesias, Ester Vázquez, Giada Cellot, Laura Ballerini, Valentina Castagnola, Fabio Benfenati, Andrea Armirotti, Antoine Sallustrau, Mathilde Keck, Frédéric Taran, Cyrill Bussy, Sandra Vranic, Kostas Kostarelos, Mona Connolly, José Maria Navas, Florence Mouchet, Laury Gauthier, James Baker, Blanca Suarez-Merino, Tomi Kanerva, Maurizio Prato, Bengt Fadeel*, Alberto Bianco*

FULL ABSTRACT

Nature Reviews Electrical Engineering, 2024, in press

Clinical translation of graphene-based medical technology

Kostas Kostarelos, Carolina Aguilar, and Jose Garrido*

FULL ABSTRACT

Nature Nanotechnology 2024, in press [https://doi.org/10.1038/s41565-023-01570-5]

Nanoporous graphene-based thin-film microelectrodes for in vivo high-resolution neural recording and stimulation

Damià Viana^, Steven T. Walston^, Eduard Masvidal-Codina^, Xavier Illa, Bruno Rodríguez-Meana, Jaume del Valle, Andrew Hayward, Abbie Dodd, Thomas Loret, Elisabet Prats-Alfonso, Natàlia de la Oliva, Marie Palma, Elena del Corro, María del Pilar Bernicola, Elisa Rodríguez-Lucas, Thomas A. Gener, Jose Manuel de la Cruz, Miguel Torres-Miranda, Fikret Taygun Duvan, Nicola Ria, Justin Sperling, Sara Martí-Sánchez, Maria Chiara Spadaro, Clément Hébert, Sinead Savage, Jordi Arbiol, Anton Guimerà-Brunet, M. Victoria Puig, Blaise Yvert, Xavier Navarro, Kostas Kostarelos*, Jose A. Garrido*

FULL ABSTRACT

bioRxiv, 2024, doi.org/10.1101/2023.09.18.558196

Engineering the glioblastoma microenvironment using TLR7/8 agonist-complexed graphene oxide nanosheets

Maria Stylianou, Thomas Kisby*, Despoina Despotopoulou, Helen Parker, Alexandra Thawley, Kiana Arashvand, Neus Lozano, Andrew MacDonald, Kostas Kostarelos*

FULL ABSTRACT

ACS Nano, 2023, 17 (24): 24919–24935

Pulmonary toxicity of boron nitride nanomaterials is aspect ratio dependent

Luis Visani^, Thomas Loret^, Yilin He, Morgan Legnani, Hazel Lin, Anne Marie Galibert, Alexander Fordham, Sonja Holme, Antonio Castillo, Francesco Bonaccorso, Alberto Bianco*, Emmanuel Flahaut*, Kostas Kostarelos*, Cyrill Bussy*

FULL ABSTRACT

Nanoscale, 2023, published online [https://doi.org/10.1039/D3NR04490D]

Delivery of graphene oxide nanosheets modulates glutamate release and normalizes amygdala synaptic plasticity to improve anxiety-related behavior

Elisa Pati, Audrey Franceschi Biagioni, Raffaele Casani, Neus Lozano, Kostas Kostarelos, Giada Cellot*, Laura Ballerini*

FULL ABSTRACT

Chemistry - A European Journal, 2023, e202301762

Graphene oxide nanosheets hamper glutamate mediated excitotoxicity and protect neuronal survival in an in vitro stroke model

Lorenza Tortella, Irene Santini, Neus Lozano, Kostas Kostarelos, Giada Cellot*, Laura Ballerini*

FULL ABSTRACT

bioRxiv, 2023, doi.org/10.1101/2023.08.22.553542

Engineering of a graphene oxide-based two-dimensional platform for immune activation and modulation

Despoina Despotopoulou, Maria Stylianou, Luis Miguel Arellano, Thomas Kisby, Neus Lozano, Kostas Kostarelos*

FULL ABSTRACT

RECENT NEWSVIEW ALL

30/10/2024

CNTM hosts the University’s new President and Vice-Chancellor Prof Duncan Ivison

READ MORE

17/10/2024

University partners with new national research hub which is revolutionising healthcare

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